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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：530929
- cas：1383719-97-8
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 530929 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 5.0mg; 25.0mg; |
| CAS編號(hào) | 1383719-97-8 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: PF-04628935 is is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 nM. Ghrelin and GSHR are involved in regulation of food intake and long-term energy homeostasis; GSHR ligands are of interest for obesity and other metabolic disorders. PF-04628935 is orally bioavailable and brain penetrant.
Name: PF-04628935
CAS#: 1383719-97-8
Chemical Formula: C24H26ClN7OS
Exact Mass: 495.1608
Molecular Weight: 496.03
Elemental Analysis: C, 58.11; H, 5.28; Cl, 7.15; N, 19.77; O, 3.23; S, 6.46
Synonym: PF-04628935; PF04628935; PF 04628935; PF-4628935; PF4628935; PF 4628935.
IUPAC/Chemical Name: 1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
InChi Key: MTDYDDJVCIHZKH-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H26ClN7OS/c1-17-12-31-14-19(28-23(31)34-17)10-22(33)30-8-4-24(5-9-30)15-29(16-24)13-18-2-3-20(11-21(18)25)32-26-6-7-27-32/h2-3,6-7,11-12,14H,4-5,8-10,13,15-16H2,1H3
SMILES Code: CC1=CN2C(S1)=NC(CC(N(CC3)CCC43CN(CC5=CC=C(N6N=CC=N6)C=C5Cl)C4)=O)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
