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Paclitaxel-Succinic acid
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:620101
  • cas:117527-50-1
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 620101
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg;
CAS編號 117527-50-1
純度 >98%%
是否進(jìn)口

Description: Paclitaxel-Succinic acid, also known as Paclitaxel Succinate or Paclitaxel-hemisuccinic acid, is a paclitaxel derivative with a succinic acid linker. The carboxy group of Paclitaxel-Succinic acid, after activiating, can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. Note: DCN10809, also known as Paclitaxel succinate NHS ester (Cat#408092) is also in stock.

Name: Paclitaxel-Succinic acid
CAS#: 117527-50-1
Chemical Formula: C51H55NO17
Exact Mass: 953.347
Molecular Weight: 953.99
Elemental Analysis: C, 64.21; H, 5.81; N, 1.47; O, 28.51

Synonym: Paclitaxel-Succinic acid; Paclitaxel Succinate; Paclitaxel-hemisuccinic acid; Paclitaxel-SA;

IUPAC/Chemical Name: 4-(((1S,2R)-1-benzamido-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-diacetoxy-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-3-oxo-1-phenylpropan-2-yl)oxy)-4-oxobutanoic acid

InChi Key: RBNOJYDPFALIQZ-LAVNIZMLSA-N

InChi Code: InChI=1S/C51H55NO17/c1-27-33(66-47(62)41(67-37(58)23-22-36(56)57)39(30-16-10-7-11-17-30)52-45(60)31-18-12-8-13-19-31)25-51(63)44(68-46(61)32-20-14-9-15-21-32)42-49(6,34(55)24-35-50(42,26-64-35)69-29(3)54)43(59)40(65-28(2)53)38(27)48(51,4)5/h7-21,33-35,39-42,44,55,63H,22-26H2,1-6H3,(H,52,60)(H,56,57)/t33-,34-,35+,39-,40+,41+,42-,44-,49+,50-,51+/m0/s1

SMILES Code: [H][C@@]1([C@@H]([C@@](C2(C)C)(C[C@@H](C(C)=C2[C@H](C([C@]([C@H](C[C@]34[H])O)1C)=O)OC(C)=O)OC([C@@H]([C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)OC(CCC(O)=O)=O)=O)O)OC(C7=CC=CC=C7)=O)[C@@]3(CO4)OC(C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001