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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：207115
- cas：1800487-55-1
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 207115 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; |
| CAS編號(hào) | 1800487-55-1 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.
Name: OT-82
CAS#: 1800487-55-1 (free base)
Chemical Formula: C26H21FN4O
Exact Mass: 424.1699
Molecular Weight: 424.4794
Elemental Analysis: C, 73.57; H, 4.99; F, 4.48; N, 13.20; O, 3.77
Synonym: OT-82; OT 82; OT82; NAMPTi OT-82; nicotinamide phosphoribosyl transferase inhibitor OT-82;
IUPAC/Chemical Name: N-(3-(1H-pyrazol-4-yl)propyl)-3-((4-fluorophenyl)ethynyl)-4-(pyridin-4-yl)benzamide
InChi Key: CEPAXRIKSUXHHB-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H21FN4O/c27-24-8-4-19(5-9-24)3-6-22-16-23(7-10-25(22)21-11-14-28-15-12-21)26(32)29-13-1-2-20-17-30-31-18-20/h4-5,7-12,14-18H,1-2,13H2,(H,29,32)(H,30,31)
SMILES Code: O=C(C1=CC(C#CC2=CC=C(C=C2)F)=C(C=C1)C3=CC=NC=C3)NCCCC4=CNN=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
