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- 品牌:MedKoo
- 產(chǎn)地:美國
- 貨號:561732
- cas:88039-46-7
- 發(fā)布日期: 2022-07-20
- 更新日期: 2024-08-12
產(chǎn)地 | 美國 |
品牌 | MedKoo |
貨號 | 561732 |
用途 | This product is for research use only, not for human or veterinary use. |
包裝規(guī)格 | 10.0mg; |
CAS編號 | 88039-46-7 |
純度 | >98%% |
是否進(jìn)口 | 是 |
Description: NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
Name: NLRP3-IN-9
CAS#: 88039-46-7
Chemical Formula: C12H13ClO3
Exact Mass: 240.0553
Molecular Weight: 240.68
Elemental Analysis: C, 59.88; H, 5.44; Cl, 14.73; O, 19.94
Synonym: NLRP3-IN-9; NLRP3 IN 9; NLRP3IN9; INF-4E; INF 4E; INF4E;
IUPAC/Chemical Name: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate
InChi Key: BSRPDXCMAOIUOO-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H13ClO3/c1-3-16-12(15)8(2)11(14)9-6-4-5-7-10(9)13/h4-7,11,14H,2-3H2,1H3
SMILES Code: C=C(C(C1=CC=CC=C1Cl)O)C(OCC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001