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NLRP3-IN-9
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:561732
  • cas:88039-46-7
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 561732
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 10.0mg;
CAS編號 88039-46-7
純度 >98%%
是否進(jìn)口

Description: NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

Name: NLRP3-IN-9
CAS#: 88039-46-7
Chemical Formula: C12H13ClO3
Exact Mass: 240.0553
Molecular Weight: 240.68
Elemental Analysis: C, 59.88; H, 5.44; Cl, 14.73; O, 19.94

Synonym: NLRP3-IN-9; NLRP3 IN 9; NLRP3IN9; INF-4E; INF 4E; INF4E;

IUPAC/Chemical Name: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate

InChi Key: BSRPDXCMAOIUOO-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H13ClO3/c1-3-16-12(15)8(2)11(14)9-6-4-5-7-10(9)13/h4-7,11,14H,2-3H2,1H3

SMILES Code: C=C(C(C1=CC=CC=C1Cl)O)C(OCC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001