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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：532343
- cas：104869-26-3
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 532343 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 10.0mg; 50.0mg; |
| CAS編號(hào) | 104869-26-3 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: NF157 is a purinergic receptor antagonist that potently inhibits P2Y11 receptor activity (IC50 = 463 nM). NF157 displays selectivity for P2Y11 and P2X1 receptors over P2Y1, P2Y2 , P2X2, P2X3, P2X4 and P2X7 receptors. NF157 also inhibits NAD+-induced activation of human granulocytes.
Name: NF157
CAS#: 104869-26-3
Chemical Formula: C49H34F2N6O23S6
Exact Mass: 1303.9968
Molecular Weight: 1305.19
Elemental Analysis: C, 45.09; H, 2.63; F, 2.91; N, 6.44; O, 28.19; S, 14.74
Synonym: NF157; NF 157; NF-157.
IUPAC/Chemical Name: 8-[[4-fluoro-3-[[3-[[3-[[2-fluoro-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid
InChi Key: UDVIAMRWOLIUAE-UHFFFAOYSA-N
InChi Code: InChI=1S/C49H34F2N6O23S6/c50-33-9-7-25(47(60)54-35-11-13-39(83(69,70)71)31-19-29(81(63,64)65)21-41(43(31)35)85(75,76)77)17-37(33)56-45(58)23-3-1-5-27(15-23)52-49(62)53-28-6-2-4-24(16-28)46(59)57-38-18-26(8-10-34(38)51)48(61)55-36-12-14-40(84(72,73)74)32-20-30(82(66,67)68)22-42(44(32)36)86(78,79)80/h1-22H,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)
SMILES Code: O=S(C1=C2C(NC(C3=CC=C(F)C(NC(C4=CC=CC(NC(NC5=CC=CC(C(NC6=CC(C(NC7=C8C(S(=O)(O)=O)=CC(S(=O)(O)=O)=CC8=C(S(=O)(O)=O)C=C7)=O)=CC=C6F)=O)=C5)=O)=C4)=O)=C3)=O)=CC=C(S(=O)(O)=O)C2=CC(S(=O)(O)=O)=C1)(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
