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- 品牌：MedKoo
- 產地：美國
- 貨號：464340
- cas：1189699-70-4
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 464340 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 1.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 2.0g; |
| CAS編號 | 1189699-70-4 |
| 純度 | >98%% |
| 是否進口 | 是 |
Description: Methocarbamol-d5 is intended for use as an internal standard for the quantification of methocarbamol by GC- or LC-MS. Methocarbamol is an orally bioavailable skeletal muscle relaxant. In vivo, methocarbamol inhibits the ability of mice to remain on a vertical ladder for 1 minute (ED50 = 15 mg/kg) and decreases forelimb grip strength by 35.9% when administered at a dose of 500 mg/kg. It abolishes femoral nerve-stimulated polysynaptic reflex contractions of the cat tibialis anterior muscle and prolongs the mean refractory period of directly or indirectly stimulated skeletal muscle when administered at a dose of 200 mg/kg. Methocarbamol also selectively inhibits human carbonic anhydrase (CA) isoform I over CAII (IC50s = 70 and ~80,000 μM, respectively). Formulations containing methocarbamol have been used to treat skeletal muscle spasms.
Name: Methocarbamol-d5
CAS#: 1189699-70-4
Chemical Formula: C11H10D5NO5
Exact Mass: 246.1264
Molecular Weight: 246.2735
Elemental Analysis: C, 53.65; H, 8.18; N, 5.69; O, 32.48
Synonym: Methocarbamol-d5; Methocarbamol d5; AHR 85-d5; AHR85-d5; AHR-85-d5; Guaiacol Glyceryl Ether Carbamate-d5; Guaiphenesin Carbamate-d5;
IUPAC/Chemical Name: 2-hydroxy-3-(2-methoxyphenoxy)propyl-1,1,2,3,3-d5 carbamate
InChi Key: GNXFOGHNGIVQEH-RORPNYJOSA-N
InChi Code: InChI=1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14)/i6D2,7D2,8D
SMILES Code: NC(OC([2H])(C([2H])(C([2H])(OC1=C(OC)C=CC=C1)[2H])O)[2H])=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
