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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：407431
- cas：2058116-52-0
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 407431 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 25.0g; 100.0g; |
| CAS編號 | 2058116-52-0 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: MDVN1003 is a potent inhibitor of BTK amd PI3K delta. MDVN1003 inhibits Bruton's tyrosine kinase (BTK) and phosphatidylinositol-3-kinase delta (PI3Kδ), two proteins regulated by the B cell receptor (BCR) that drive the growth of many NHLs. MDVN1003 induces cell death in a B cell lymphoma cell line but not in an irrelevant erythroblast cell line.
Name: MDVN1003
CAS#: 2058116-52-0
Chemical Formula: C22H20FN7O
Exact Mass: 417.1713
Molecular Weight: 417.4484
Elemental Analysis: C, 63.30; H, 4.83; F, 4.55; N, 23.49; O, 3.83
Synonym: MDVN1003; MDVN-1003; MDVN 1003.
IUPAC/Chemical Name: 1-(5-amino-2,3-dihydro-1H-inden-2-yl)-3-(8-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChi Key: ULJLSBKQZMEISX-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H20FN7O/c23-16-8-13(9-17-20(16)31-4-3-26-17)19-18-21(25)27-10-28-22(18)30(29-19)15-6-11-1-2-14(24)5-12(11)7-15/h1-2,5,8-10,15,26H,3-4,6-7,24H2,(H2,25,27,28)
SMILES Code: NC1=C2C(N(C3CC(C=CC(N)=C4)=C4C3)N=C2C5=CC(NCCO6)=C6C(F)=C5)=NC=N1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
