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MDK-8650
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):555458
  • cas:736048-65-0
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 555458
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g;
CAS編號(hào) 736048-65-0
純度 >98%%
是否進(jìn)口

Description: MDK-8650, also known as PKC-theta inhibitor, is a selective PKC-θinhibitor, with an IC50 of 12 nM.

Name: MDK-8650
CAS#: 736048-65-0
Chemical Formula: C20H25F3N6O3
Exact Mass: 454.194
Molecular Weight: 454.4542
Elemental Analysis: C, 52.86; H, 5.55; F, 12.54; N, 18.49; O, 10.56

Synonym: MDK-8650; MDK 8650; MDK8650; PKC-theta inhibitor;

IUPAC/Chemical Name: N4-((4-(aminomethyl)cyclohexyl)methyl)-5-nitro-N2-(2-(trifluoromethoxy)benzyl)pyrimidine-2,4-diamine

InChi Key: HKOWATVSFKRXRW-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H25F3N6O3/c21-20(22,23)32-17-4-2-1-3-15(17)11-26-19-27-12-16(29(30)31)18(28-19)25-10-14-7-5-13(9-24)6-8-14/h1-4,12-14H,5-11,24H2,(H2,25,26,27,28)

SMILES Code: FC(F)(F)OC1=CC=CC=C1CNC2=NC=C([N+]([O-])=O)C(NCC3CCC(CN)CC3)=N2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001