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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：464558
- cas：1387005-23-3
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 464558 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; |
| CAS編號 | 1387005-23-3 |
| 純度 | >98%% |
| 是否進口 | 是 |
Description: LDN-05233 is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3. It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, LDN-05233 is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. LDN-05233 displays excitation/emission maxima of 340-360/440-460 nm, respectively. This product has no formal name at the moment.
Name: LDN-05233
CAS#: 1387005-23-3
Chemical Formula: C36H52N8O9
Exact Mass: 740.3857
Molecular Weight: 740.859
Elemental Analysis: C, 58.36; H, 7.08; N, 15.13; O, 19.44
Synonym: LDN-05233; LDN05233; LDN 05233; Ac-QPKK(Ac)-AMC;
IUPAC/Chemical Name: (S)-N-((S)-1-(((S)-6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)amino)-6-amino-1-oxohexan-2-yl)-1-(acetyl-L-glutaminyl)pyrrolidine-2-carboxamide
InChi Key: LHVYYJGFOAKRPP-DZUOILHNSA-N
InChi Code: InChI=1S/C36H52N8O9/c1-21-19-32(48)53-30-20-24(12-13-25(21)30)41-33(49)26(10-5-7-17-39-22(2)45)42-34(50)27(9-4-6-16-37)43-35(51)29-11-8-18-44(29)36(52)28(40-23(3)46)14-15-31(38)47/h12-13,19-20,26-29H,4-11,14-18,37H2,1-3H3,(H2,38,47)(H,39,45)(H,40,46)(H,41,49)(H,42,50)(H,43,51)/t26-,27-,28-,29-/m0/s1
SMILES Code: NCCCC[C@H](NC([C@@H]1CCCN1C([C@@H](NC(C)=O)CCC(N)=O)=O)=O)C(N[C@@H](CCCCNC(C)=O)C(NC2=CC=C3C(C)=CC(OC3=C2)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
