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KUS121
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:461979
  • cas:1357164-52-3
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 461979
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 1.0mg; 5.0mg; 10.0mg;
CAS編號 1357164-52-3
純度 >98%%
是否進(jìn)口

Description: KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity. It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, an inducer of ER stress, in HeLa cells.

Name: KUS121
CAS#: 1357164-52-3
Chemical Formula: C22H16FN4NaO3S
Exact Mass: 458.0825
Molecular Weight: 458.4432
Elemental Analysis: C, 57.64; H, 3.52; F, 4.14; N, 12.22; Na, 5.01; O, 10.47; S, 6.99

Synonym: KUS121; KUS-121; KUS 121;

IUPAC/Chemical Name: 4-amino-3-[2-[6-(4-fluoro-2-methylphenyl)-3-pyridinyl]diazenyl]-1-naphthalenesulfonic acid, monosodium salt

InChi Key: OEEZHMGRDYLKGJ-JGUILPGDSA-M

InChi Code: InChI=1S/C22H17FN4O3S.Na/c1-13-10-14(23)6-8-16(13)19-9-7-15(12-25-19)26-27-20-11-21(31(28,29)30)17-4-2-3-5-18(17)22(20)24;/h2-12H,24H2,1H3,(H,28,29,30);/q;+1/p-1/b27-26+;

SMILES Code: O=S(C1=C2C=CC=CC2=C(N)C(/N=N/C3=CC=C(C4=CC=C(F)C=C4C)N=C3)=C1)([O-])=O.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001