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K-756
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:558248
  • cas:130017-40-2
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 558248
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 5.0mg; 25.0mg;
CAS編號 130017-40-2
純度 >98%%
是否進口

Description: K-756 is a a selective Wnt/β-catenin pathway inhibitor. K-756 is also a tankyrase (TNKS) inhibitor. K-756 binds to the induced pocket of TNKS and inhibits its enzyme activity. could be a leading compound in the development of anticancer agents.

Name: K-756
CAS#: 130017-40-2
Chemical Formula: C24H27N5O3
Exact Mass: 433.2114
Molecular Weight: 433.51
Elemental Analysis: C, 66.50; H, 6.28; N, 16.16; O, 11.07

Synonym: K-756; K 756; K756;

IUPAC/Chemical Name: 3-[1-(6,7-Dimethoxy-quinazolin-4-yl)-piperidin-4-ylmethyl]-3,4-dihydro-1H-quinazolin-2-one

InChi Key: GWXCGEJJQFHPPA-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H27N5O3/c1-31-21-11-18-20(12-22(21)32-2)25-15-26-23(18)28-9-7-16(8-10-28)13-29-14-17-5-3-4-6-19(17)27-24(29)30/h3-6,11-12,15-16H,7-10,13-14H2,1-2H3,(H,27,30)

SMILES Code: O=C1NC2=C(C=CC=C2)CN1CC3CCN(C4=C5C=C(OC)C(OC)=CC5=NC=N4)CC3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001