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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：540228
- cas：1913252-04-6
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 540228 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS編號(hào) | 1913252-04-6 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: JQ-EZ-05, also known as JQEZ5 is a Potent and selective SAM-competitive EZH2 inhibitor (IC50 = 11 nM). JQ-EZ-05 selectively binds EZH2 over a panel of 22 methyltransferases.
Name: JQ-EZ-05
CAS#: 1913252-04-6
Chemical Formula: C30H38N8O2
Exact Mass: 542.3118
Molecular Weight: 542.68
Elemental Analysis: C, 66.40; H, 7.06; N, 20.65; O, 5.90
Synonym: JQEZ5; JQEZ-5; JQEZ 5; JQ-EZ-05; JQ-EZ05; JQ-EZ 05;
IUPAC/Chemical Name: 1-isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
InChi Key: LQTWDAYNGMMHLV-UHFFFAOYSA-N
InChi Code: InChI=1S/C30H38N8O2/c1-6-7-21-14-20(4)34-30(40)24(21)17-32-29(39)23-15-26(35-28-25(23)18-33-38(28)19(2)3)22-8-9-27(31-16-22)37-12-10-36(5)11-13-37/h8-9,14-16,18-19H,6-7,10-13,17H2,1-5H3,(H,32,39)(H,34,40)
SMILES Code: CC(C)N1N=CC2=C(C=C(N=C12)C3=CC=C(N4CCN(CC4)C)N=C3)C(NCC5=C(CCC)C=C(C)NC5=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
