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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：206446
- cas：1383547-60-1
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 206446 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 1.0g; 2.0g; 5.0g; |
| CAS編號 | 1383547-60-1 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphorbia peplus and an inducer of cell death.
Name: Ingenol disoxate
CAS#: 1383547-60-1
Chemical Formula: C28H37NO7
Exact Mass: 499.257
Molecular Weight: 499.6
Elemental Analysis: C, 67.31; H, 7.47; N, 2.80; O, 22.42
Synonym: Ingenol disoxate; LEO43204; LEO 43204; LEO-43204.
IUPAC/Chemical Name: (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-6-yl 3,5-diethylisoxazole-4-carboxylate
InChi Key: GLIUZQUNUNICGS-XUBYYPQFSA-N
InChi Code: InChI=1S/C28H37NO7/c1-7-18-20(19(8-2)36-29-18)25(33)35-24-13(3)11-27-14(4)9-17-21(26(17,5)6)16(23(27)32)10-15(12-30)22(31)28(24,27)34/h10-11,14,16-17,21-22,24,30-31,34H,7-9,12H2,1-6H3/t14-,16+,17-,21+,22-,24+,27+,28+/m1/s1
SMILES Code: [H][C@]1(C[C@H]2C)C(C)([C@@]([C@@](C([C@]23C=C([C@@H]([C@@]43O)OC(C5=C(CC)ON=C5CC)=O)C)=O)(C=C([C@H]4O)CO)[H])1[H])C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
