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GUN30820
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):555945
  • cas:2104030-82-0
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 555945
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 200.0mg; 500.0mg; 1.0g; 2.0g;
CAS編號(hào) 2104030-82-0
純度 >98%%
是否進(jìn)口

Description: GUN30820, also known as Brr2 inhibitor C9 or Brr2 Inhibitor 9, is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa a group of progressive retinal degenerative disorders. GUN30820 was first described in Journal of Medicinal Chemistry (2017), 60(13), 5759-5771. 

Name: GUN30820
CAS#: 2104030-82-0
Chemical Formula: C24H20N4O3S
Exact Mass: 444.1256
Molecular Weight: 444.509
Elemental Analysis: C, 64.85; H, 4.54; N, 12.60; O, 10.80; S, 7.21

Synonym: Brr2 inhibitor C9; Brr2 Inhibitor 9; Brr2-IN-3; GUN30820; GUN-30820; GUN 30820;

IUPAC/Chemical Name: 6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione

InChi Key: GAWVULNDIBAUHU-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H20N4O3S/c29-23-10-22-18(13-27(23)12-17-5-2-1-3-6-17)14-28(24(30)26-22)19-7-4-8-20(9-19)31-15-21-11-25-16-32-21/h1-11,13,16H,12,14-15H2,(H,26,30)

SMILES Code: O=C1NC(C(CN1C2=CC=CC(OCC3=CN=CS3)=C2)=CN4CC5=CC=CC=C5)=CC4=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001