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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：531884
- cas：929095-23-8
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 531884 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 1.0mg; 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; |
| CAS編號(hào) | 929095-23-8 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: GSK579289A is an inhibitor of polo-like kinase 1 (Plk1; IC50 = 2 nM). It is selective for Plk1 over Plk3 (IC50 = 630 nM). GSK579289A inhibits proliferation of HCT116 cells (IC50 = 11 nM).
Name: GSK579289A
CAS#: 929095-23-8
Chemical Formula: C26H27ClN4O3S
Exact Mass: 510.1492
Molecular Weight: 511.04
Elemental Analysis: C, 61.11; H, 5.33; Cl, 6.94; N, 10.96; O, 9.39; S, 6.27
Synonym: GSK579289A; GSK 579289A; GSK-579289A.
IUPAC/Chemical Name: 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[6-(1-methylpiperidin-4-yl)oxybenzimidazol-1-yl]thiophene-2-carboxamide
InChi Key: GILNGUYOGYOZMP-MRXNPFEDSA-N
InChi Code: InChI=1S/C26H27ClN4O3S/c1-16(19-5-3-4-6-20(19)27)33-23-14-24(35-25(23)26(28)32)31-15-29-21-8-7-18(13-22(21)31)34-17-9-11-30(2)12-10-17/h3-8,13-17H,9-12H2,1-2H3,(H2,28,32)/t16-/m1/s1
SMILES Code: O=C(C1=C(O[C@@H](C2=CC=CC=C2Cl)C)C=C(N3C4=CC(OC5CCN(C)CC5)=CC=C4N=C3)S1)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
