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Gracillin
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):471002
  • cas:19083-00-2
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 471002
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 5.0mg; 10.0mg; 25.0mg;
CAS編號(hào) 19083-00-2
純度 >98%%
是否進(jìn)口

Description: Gracillin is a steroidal saponin that has been found in C. speciosus and has diverse biological activities. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1.

Synonym: Gracillin; NSC-698787; NSC 698787; NSC698787;

IUPAC/Chemical Name: (2S,3R,4S,5R,6R)-2-(((2R,3R,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aR,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)-5-(((2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

InChi Key: YQEMAEKYNNOCBY-JFFBLZSISA-N

InChi Code: InChI=1S/C45H72O17/c1-19-8-13-45(55-18-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-40-36(53)34(51)31(48)21(3)56-40)38(33(50)29(17-47)59-42)60-41-37(54)35(52)32(49)28(16-46)58-41/h6,19-21,23-42,46-54H,7-18H2,1-5H3/t19-,20+,21-,23+,24-,25+,26+,27+,28-,29-,30+,31+,32+,33-,34-,35+,36-,37-,38+,39-,40+,41+,42-,43+,44-,45-/m1/s1

SMILES Code: O1[C@H]([C@H](O)[C@H]([C@@H](O)[C@H]1CO)O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O[C@H]1[C@H](O)[C@H](O)[C@H]([C@@H](C)O1)O)O[C@H]1CC[C@@]2([C@H]3CC[C@@]4([C@H]([C@@H]3CC=C2C1)C[C@H]1[C@@H]4[C@H](C)[C@]2(O1)CC[C@@H](C)CO2)C)C)CO)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00