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GGTI-2133
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):555193
  • cas:191102-79-1
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 555193
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 1.0mg; 5.0mg;
CAS編號(hào) 191102-79-1
純度 >98%%
是否進(jìn)口

Description: GGTI-2133 is a peptidomimetic inhibitor of geranylgeranyl transferase type I (GGTase I; IC50 = 38 nM). GGTI-2133 inhibits infiltration of inflammatory cells into airways in mouse experimental asthma. GGTI-2133 increase erythrocyte deformability but reduce low O(2) tension-induced ATP release.

Name: GGTI-2133
CAS#: 191102-79-1
Chemical Formula: C27H28N4O3
Exact Mass: 456.2161
Molecular Weight: 456.546
Elemental Analysis: C, 71.03; H, 6.18; N, 12.27; O, 10.51

Synonym: GGTI 2133; GGTI-2133; GGTI2133.

IUPAC/Chemical Name: N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-L-leucine

InChi Key: ODTFPKNIFYMEHP-VWLOTQADSA-N

InChi Code: InChI=1S/C27H28N4O3/c1-17(2)12-25(27(33)34)31-26(32)23-11-10-19(29-15-20-14-28-16-30-20)13-24(23)22-9-5-7-18-6-3-4-8-21(18)22/h3-11,13-14,16-17,25,29H,12,15H2,1-2H3,(H,28,30)(H,31,32)(H,33,34)/t25-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)NC(C1=CC=C(NCC2=CN=CN2)C=C1C3=C4C=CC=CC4=CC=C3)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001