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GB1107
  • 品牌:MedKoo
  • 產(chǎn)地:美國(guó)
  • 貨號(hào):207088
  • cas:1978336-61-6
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 美國(guó)
品牌 MedKoo
貨號(hào) 207088
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 5.0mg; 10.0mg; 50.0mg; 100.0mg;
CAS編號(hào) 1978336-61-6
純度 >98%%
是否進(jìn)口

Description: GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM. GB1107 Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.

Name: GB1107
CAS#: 1978336-61-6
Chemical Formula: C20H16Cl2F3N3O4S
Exact Mass: 521.0191
Molecular Weight: 522.3202
Elemental Analysis: C, 45.99; H, 3.09; Cl, 13.57; F, 10.91; N, 8.05; O, 12.25; S, 6.14

Synonym: GB1107; GB-1107; GB 1107;

IUPAC/Chemical Name: 3,4-dichlorophenyl 3-deoxy-3-[4(3,4,5-trifluorophenyl)-1H-1,2,3- triazol-1-yl]-1-thio-α-D-galactopyranoside

InChi Key: CSGJIUAIYDKFPC-DABHTEOTSA-N

InChi Code: InChI=1S/C20H16Cl2F3N3O4S/c21-10-2-1-9(5-11(10)22)33-20-19(31)17(18(30)15(7-29)32-20)28-6-14(26-27-28)8-3-12(23)16(25)13(24)4-8/h1-6,15,17-20,29-31H,7H2/t15-,17+,18+,19-,20-/m1/s1

SMILES Code: O[C@H]([C@@H](N1N=NC(C2=CC(F)=C(F)C(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@H]3SC4=CC=C(Cl)C(Cl)=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001