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Fluocinonide
  • 品牌：MedKoo
  • 產(chǎn)地：美國
  • 貨號：317888
  • cas：356-12-7
  • 發(fā)布日期： 2022-07-20
  • 更新日期： 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 317888
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 100.0mg; 250.0mg;
CAS編號 356-12-7
純度 >98%%
是否進口 是
Description: Fluocinonide is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. Fluocinonide ranks as a "high-potency" (second-highest rank) topical corticosteroid. Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis (HPA) suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.

Synonym: Fluocinonide, Lidex, Fluocinolide, Lyderm, Metosyn, Topsyn, Vanos, Lonide

IUPAC/Chemical Name: 2-((2S,6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-2,6b-difluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoethyl acetate

InChi Key: WJOHZNCJWYWUJD-IUGZLZTKSA-N

InChi Code: InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1

SMILES Code: CC(OCC([C@@]12[C@H](OC(C)(C)O2)C[C@@H]3[C@]1(C)C[C@H](O)[C@@]4(F)[C@H]3C[C@H](F)C5=CC(C=C[C@@]54C)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001