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- 品牌：MedKoo
- 產地：美國
- 貨號：206440
- cas：1346242-81-6
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 206440 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g; |
| CAS編號 | 1346242-81-6 |
| 純度 | >98%% |
| 是否進口 | 是 |
產品簡介：厄達替尼，也稱為JNJ-42756493，是一種有效且選擇性的口服生物利用性泛成纖維細胞生長因子受體（FGFR）抑制劑，具有潛在的抗腫瘤活性?？诜o藥后，JNJ-42756493結合并抑制FGFR，這可能導致抑制FGFR相關信號轉導途徑，從而抑制FGFR過表達腫瘤細胞中的腫瘤細胞增殖和腫瘤細胞死亡。FGFR在許多腫瘤細胞類型中上調，是一種對腫瘤細胞增殖、分化和存活至關重要的受體酪氨酸激酶。
產品名稱: Erdafitinib
CAS#: 1346242-81-6
分子式: C25H30N6O2
Exact Mass: 446.24302
分子量: 446.55
元素分析: C, 67.24; H, 6.77; N, 18.82; O, 7.17
Synonym: JNJ-42756493; JNJ 42756493; JNJ42756493; Erdafitinib
IUPAC/Chemical Name: N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
InChi Key: OLAHOMJCDNXHFI-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3
SMILES Code: CC(NCCN(C1=CC(OC)=CC(OC)=C1)C2=CC=C3N=CC(C4=CN(C)N=C4)=NC3=C2)C
Appearance: Yellow solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
