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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：561112
- cas：868046-19-9
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 561112 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS編號 | 868046-19-9 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of human immunodeficiency virus (HIV) infections. It is the prodrug of the active compound VM-1500A, a small molecule selective NNRTI, which prevents HIV replication. In June 2017, elsulfavirine received its first global approval in Russia for the treatment of HIV-1 infections in combination with other antiretroviral medicines. Other formulations of this drug are also being evaluated in preclinical and phase II studies for the treatment of HIV infections and/or pre-exposure and post-exposure prophylaxis.
Name: Elsulfavirine
CAS#: 868046-19-9
Chemical Formula: C24H17BrCl2FN3O5S
Exact Mass: 626.9433
Molecular Weight: 629.28
Elemental Analysis: C, 45.81; H, 2.72; Br, 12.70; Cl, 11.27; F, 3.02; N, 6.68; O, 12.71; S, 5.09
Synonym: Elsulfavirine; Elpida.
IUPAC/Chemical Name: N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide
InChi Key: ULTDEARCBRNRGR-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H17BrCl2FN3O5S/c1-2-21(32)31-37(34,35)17-4-6-20(19(27)11-17)30-22(33)9-14-3-5-18(25)24(23(14)28)36-16-8-13(12-29)7-15(26)10-16/h3-8,10-11H,2,9H2,1H3,(H,30,33)(H,31,32)
SMILES Code: CCC(NS(=O)(C1=CC=C(NC(CC2=CC=C(Br)C(OC3=CC(C#N)=CC(Cl)=C3)=C2F)=O)C(Cl)=C1)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
