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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號(hào)：463118
- cas：119-13-1
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號(hào) | 463118 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS編號(hào) | 119-13-1 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: D-δ-Tocopherol is a biologically active form of vitamin E, a lipid-soluble antioxidant that protects cellular membranes from oxidative damage. It reduces cumene hydroperoxide-induced lipid peroxidation in hepatocytes when used at a concentration of 20 μM but induces lipid peroxidation in hepatic microsomes at 100 μM. D-δ-Tocopherol decreases capillary formation of HMEC-1 blood endothelial cells. It also decreases the expression of VCAM in, and the invasiveness of, HMEC-1 cells. D-δ-Tocopherol reduces estrogen-induced increases in the expression of the estrogen-responsive genes encoding TFF/pS2, cathepsin D, PGR, CITED1, and SERPINA1 and the levels of 8-hydroxy-2’-deoxyguanosine (8-oxo-dG) and nitrotyrosine in MCF-7 breast cancer cells. Dietary administration of D-δ-Tocopherol reduces tumor growth in an estrogen-supplemented MCF-7 mouse xenograft model.
Synonym: D-δ-Tocopherol; Dδ-Tocopherol; D δ-Tocopherol; D-δTocopherol; D-δ Tocopherol; DδTocopherol; D δ Tocopherol; (+)-δ-Tocopherol;
IUPAC/Chemical Name: (S)-2,8-dimethyl-2-((4S,8S)-4,8,12-trimethyltridecyl)chroman-6-ol
InChi Key: GZIFEOYASATJEH-BERHBOFZSA-N
InChi Code: InChI=1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3/t21-,22-,27-/m0/s1
SMILES Code: CC1=C2C(CC[C@@](O2)(CCC[C@H](CCC[C@H](CCCC(C)C)C)C)C)=CC(O)=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
