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Dynarrestin
  • 品牌:MedKoo
  • 產(chǎn)地:美國
  • 貨號:584582
  • cas:2222768-84-3
  • 發(fā)布日期: 2022-07-20
  • 更新日期: 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 584582
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g;
CAS編號 2222768-84-3
純度 >98%%
是否進(jìn)口

Description: Dynarrestin is a potent and selective dynein inhibitor. Dynarrestin inhibits hedgehog signaling in vitro (IC50 = 0.22 μM). Dynarrestin exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport.

Name: Dynarrestin
CAS#: 2222768-84-3
Chemical Formula: C22H23F2N3O2S
Exact Mass: 431.1479
Molecular Weight: 431.5018
Elemental Analysis: C, 61.24; H, 5.37; F, 8.81; N, 9.74; O, 7.42; S, 7.43

Synonym: Dynarrestin

IUPAC/Chemical Name: Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate

InChi Key: UZNNDDDSGCMQOQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H23F2N3O2S/c1-4-27(5-2)16-10-7-14(8-11-16)19-20(21(28)29-6-3)30-22(26-19)25-18-12-9-15(23)13-17(18)24/h7-13H,4-6H2,1-3H3,(H,25,26)

SMILES Code: O=C(C1=C(C2=CC=C(N(CC)CC)C=C2)N=C(NC3=CC=C(F)C=C3F)S1)OCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00