|
- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：464894
- cas：58142-99-7
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 464894 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS編號 | 58142-99-7 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: DSRM-3716 is a potent, reversible inhibitor of SARM1 NAD(+) hydrolase (IC50 = 75 nM), which displays selectivity for SARM1 over related enzymes NAMPT and NMNAT and a panel of receptors and transporters. In vitro, DSRM-3716 decreases cyclic adenosine diphosphate ribose (cADPR) levels in mouse dorsal root ganglia (DRG) neurons, and protects mouse DRG and iPSC-derived human motor neurons against axonal degeneration. In axons with rotenone-induced mitochondrial injury, DSRM-3716 rescues axons displaying indicators of degeneration.
Name: DSRM-3716
CAS#: 58142-99-7
Chemical Formula: C9H6IN
Exact Mass: 254.9545
Molecular Weight: 255.0585
Elemental Analysis: C, 42.38; H, 2.37; I, 49.76; N, 5.49
Synonym: DSRM-3716; DSRM3716; DSRM 3716;
IUPAC/Chemical Name: 5-iodoisoquinoline
InChi Key: CUILFTFMBBGSFT-UHFFFAOYSA-N
InChi Code: InChI=1S/C9H6IN/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-6H
SMILES Code: IC1=CC=CC2=C1C=CN=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
