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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：408092
- cas：245110-80-9
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 408092 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; |
| CAS編號 | 245110-80-9 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: DCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino group or hydroxy group, and can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. Note: Paclitaxel-Succinic acid (CAT#620101) is also in stock.
Name: DCN10809
CAS#: 245110-80-9
Chemical Formula: C55H58N2O19
Exact Mass: 1050.3634
Molecular Weight: 1051.064
Elemental Analysis: C, 62.85; H, 5.56; N, 2.67; O, 28.92
Synonym: Paclitaxel succinate NHS ester; DCN10809; DCN-10809; DCN 10809; Paclitaxel-Succinic acid NHS ester
IUPAC/Chemical Name: (1S,2R)-1-benzamido-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-diacetoxy-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-3-oxo-1-phenylpropan-2-yl (2,5-dioxopyrrolidin-1-yl) succinate
InChi Key: DXNRHBJDAAJTTD-CGFZLWGJSA-N
InChi Code: InChI=1S/C55H58N2O19/c1-29-35(72-51(68)45(73-40(63)24-25-41(64)76-57-38(61)22-23-39(57)62)43(32-16-10-7-11-17-32)56-49(66)33-18-12-8-13-19-33)27-55(69)48(74-50(67)34-20-14-9-15-21-34)46-53(6,36(60)26-37-54(46,28-70-37)75-31(3)59)47(65)44(71-30(2)58)42(29)52(55,4)5/h7-21,35-37,43-46,48,60,69H,22-28H2,1-6H3,(H,56,66)/t35-,36-,37+,43-,44+,45+,46-,48-,53+,54-,55+/m0/s1
SMILES Code: CC1(C([C@@H](OC(C)=O)C([C@@](C)([C@]23[H])[C@@H](O)C[C@]4(OC[C@]43OC(C)=O)[H])=O)=C([C@H](C[C@]1([C@H]2OC(C5=CC=CC=C5)=O)O)OC([C@H](OC(CCC(ON6C(CCC6=O)=O)=O)=O)[C@@H](NC(C7=CC=CC=C7)=O)C8=CC=CC=C8)=O)C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
