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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：462359
- cas：1226549-49-0
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 462359 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 咨詢 |
| CAS編號 | 1226549-49-0 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: DBPR112 is an orally active Furanopyrimidine-Based Epidermal Growth Factor Receptor inhibitor for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 has significant antitumor efficacy.
Name: DBPR112
CAS#: 1226549-49-0
Chemical Formula: C32H31N5O3
Exact Mass: 533.2427
Molecular Weight: 533.632
Elemental Analysis: C, 72.03; H, 5.86; N, 13.12; O, 8.99
Synonym: DBPR112; DBPR-112; DBPR 112
IUPAC/Chemical Name: (S,E)-4-(dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)but-2-enamide
InChi Key: NQAMTZUVRFRJCZ-VMMYIZNOSA-N
InChi Code: InChI=1S/C32H31N5O3/c1-37(2)18-10-17-27(39)35-25-16-9-15-24(19-25)28-29-31(36-26(20-38)22-11-5-3-6-12-22)33-21-34-32(29)40-30(28)23-13-7-4-8-14-23/h3-17,19,21,26,38H,18,20H2,1-2H3,(H,35,39)(H,33,34,36)/b17-10+/t26-/m1/s1
SMILES Code: O=C(NC1=CC=CC(C2=C(C3=CC=CC=C3)OC4=NC=NC(N[C@@H](C5=CC=CC=C5)CO)=C42)=C1)/C=C/CN(C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
