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Benzamil HCl
  • 品牌：MedKoo
  • 產(chǎn)地：美國
  • 貨號：573994
  • cas：161804-20-2
  • 發(fā)布日期： 2022-07-20
  • 更新日期： 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 573994
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 5.0mg; 10.0mg;
CAS編號 161804-20-2
純度 >98%%
是否進(jìn)口 是
Description: Benzamil HCl is a derivative of amiloride. Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from and binds to kidney cortex membrane vesicles. It is also an inhibitor of the Na+/Ca2+ exchanger (NCX) that inhibits the cytosolic calcium response to extracellular sodium depletion. Benzamil inhibits transient receptor potential polycystin-L (TRPP3) -- a member of the TRP superfamily of cation channels.

Synonym: Benzamil HCl, Benzamil Hydrochloride

IUPAC/Chemical Name: 3,5-diamino-6-chloro-N-[imino[(phenylmethyl)amino]methyl]-2-pyrazinecarboxamide, monohydrochloride

InChi Key: ZNWMRWWNJBXNKJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H14ClN7O.ClH/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7;/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22);1H

SMILES Code: ClC1=C(N)N=C(N)C(C(NC(NCC2=CC=CC=C2)=N)=O)=N1.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001