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Agomelatine
  • 品牌：MedKoo
  • 產(chǎn)地：美國
  • 貨號：315211
  • cas：138112-76-2
  • 發(fā)布日期： 2022-07-20
  • 更新日期： 2024-08-12
產(chǎn)品詳請
產(chǎn)地 美國
品牌 MedKoo
貨號 315211
用途 This product is for research use only, not for human or veterinary use.
包裝規(guī)格 500.0mg; 1.0g; 5.0g; 10.0g; 20.0g; 50.0g; 100.0g;
CAS編號 138112-76-2
純度 >98%%
是否進口 是
Description: Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep. Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. Binding studies indicate that it has no effect on monoamine uptake and no affinity for α, β adrenergic, histaminergic, cholinergic, dopaminergic and benzodiazepine receptors.

Synonym: Valdoxan; Thymanax; Melitor; AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098.

IUPAC/Chemical Name: N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

InChi Key: YJYPHIXNFHFHND-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)

SMILES Code: CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001